SCHEMBL5524320

SCHEMBL5524320

NC(=O)C1CN(c2cc(F)c(C3CCCSNC3)c(F)c2)C(=O)O1

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.50
F10 P00742 2/20 0.33
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5504825 0.88 MAOA (0.40) MAOAF10MAOB
SCHEMBL13515461 0.84 MAOA (0.59) MAOAF10MAOB
SCHEMBL3029037 0.82 MAOA (0.57) MAOAF10MAOB
SCHEMBL3038258 0.78 MAOA (0.73) MAOAF10MAOB
SCHEMBL5792952 0.78 MAOA (0.53) MAOAF10MAOB
SCHEMBL13515906 0.76 MAOA (0.56) MAOAF10MAOB
SCHEMBL4879072 0.76 MAOA (0.60) MAOAF10MAOB
SCHEMBL3034814 0.75 MAOA (0.55) MAOAF10MAOB
SCHEMBL3034811 0.75 MAOA (0.55) MAOAF10MAOB
SCHEMBL3038817 0.75 MAOA (0.55) MAOAF10MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1819702-A1 THIAZEPINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS Pharmacia & Upjohn Company LLC (US) 2007-08-22 EP disclosed
WO-2006056875-A1 THIAZEPINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-06-01 WO disclosed