Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494418 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRKMT2AMEN1GAA | |
| SCHEMBL5507874 | 0.81 | SMN1; SMN2 (0.75) | SMN1; SMN2TSHRKMT2AMEN1GAA | |
| SCHEMBL5515220 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRKMT2AMEN1GAA | |
| SCHEMBL5524642 | 0.76 | POLB (0.60) | SMN1; SMN2TSHRPOLBCTDSP1TDP1 | |
| SCHEMBL14599389 | 0.73 | SMN1; SMN2 (0.63) | SMN1; SMN2TSHRKMT2AMEN1GAA | |
| SCHEMBL5524587 | 0.73 | ALDH1A1 (0.76) | SMN1; SMN2TSHRKMT2AMEN1POLB | |
| SCHEMBL5509559 | 0.72 | POLB (0.61) | SMN1; SMN2TSHRKMT2AMEN1GAA | |
| SCHEMBL5517048 | 0.72 | GAA (0.64) | SMN1; SMN2TSHRKMT2AMEN1GAA | |
| SCHEMBL14494356 | 0.71 | SMN1; SMN2 (0.61) | SMN1; SMN2TSHRKMT2AMEN1GAA | |
| SCHEMBL11583923 | 0.70 | ALDH1A1 (0.61) | SMN1; SMN2TSHRKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-20060189771-A1 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2006-08-24 | — | — | US | disclosed |
| US-20060041092-A1 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2006-02-23 | — | — | US | disclosed |
| EP-1561766-A1 | RING-OPENED POLYNORBORNENES | JSR Corporation (JP) | 2005-08-10 | — | — | EP | disclosed |