Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18258631 | 0.98 | GPR84 (0.48) | NPSR1HSD17B10GPR84FFAR1MAPT | |
| SCHEMBL3868378 | 0.98 | GPR84 (0.48) | NPSR1HSD17B10GPR84FFAR1MAPT | |
| SCHEMBL18258587 | 0.94 | NPSR1 (0.49) | NPSR1HSD17B10GPR84FFAR1MAPT | |
| SCHEMBL18258589 | 0.94 | NPSR1 (0.49) | NPSR1HSD17B10GPR84FFAR1MAPT | |
| SCHEMBL18258632 | 0.86 | NPSR1 (0.52) | NPSR1HSD17B10MAPTPPARGMAPK1 | |
| SCHEMBL5512388 | 0.86 | NPSR1 (0.52) | NPSR1HSD17B10MAPTPPARGMAPK1 | |
| SCHEMBL11533629 | 0.81 | HSD17B10 (0.47) | NPSR1HSD17B10FFAR1MAPTPPARG | |
| SCHEMBL11536585 | 0.80 | HSD17B10 (0.46) | NPSR1HSD17B10FFAR1MAPTMAPK1 | |
| SCHEMBL11537625 | 0.80 | HSD17B10 (0.46) | NPSR1HSD17B10FFAR1MAPTMAPK1 | |
| SCHEMBL5057353 | 0.80 | NPSR1 (0.46) | NPSR1HSD17B10PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100471836-C | Crystalline forms VI and VII of atorvastatin calcium | REDDYS LAB LTD DR (IN) | 2009-03-25 | — | — | CN | claimed |
| CN-1537098-A | Crystalline forms VI and VII of atorvastatin calcium | ʵ | 2004-10-13 | — | — | CN | claimed |
| CN-1087288-C | Crystalline [R-(R',R')]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(5-methylethyl)-3-phenyl-4-(phenylamino) carbonyl]-1H-pyrole-1-heptanoic acid hemi calcium salt (atorvastatin) | WARNER LAMBERT CO (US) | 2002-07-10 | — | — | CN | claimed |
| CN-1190955-A | Crystalline [R-(R',R')]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(5-methylethyl)-3-phenyl-4-(phenylamino) carbonyl]-1H-pyrole-1-heptanoic acid hemi calcium salt (atorvastatin) | WARMER LAMBERT CO (US) | 1998-08-19 | — | — | CN | claimed |
| CN-1089614-A | Alpha-phosphonosulfonate squalene synthetase inhibitors and method | SQUIBB & SONS INC (US) | 1994-07-20 | — | — | CN | claimed |
| CN-109771650-A | The composition being made of rush histamine release object and two substituted biphenyl derivatives | 黄泳华 | 2019-05-21 | — | — | CN | disclosed |
| EP-1470258-B1 | COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS | TFL LEDERTECHNIK GMBH (DE) | 2013-08-28 | — | — | EP | disclosed |
| CN-1946687-B | Polymorphic substance of atorvastatin tert-butyl ester and application of polymorphic substance as intermediate in preparation of atorvastatin | KRKA TOVARNA ZDRAVIL D D NOVO MESTO | 2011-09-28 | — | — | CN | disclosed |
| CN-101560177-A | Preparation method of atorvastatin calcium | BEIJING WANQUAN SUNSHINE MEDIC (CN) | 2009-10-21 | — | — | CN | disclosed |
| CN-101538238-A | Polymorphs of atorvastatin tert.-butylester and use as intermediates for the preparation of atorvastatin | KRKA TOVARNA ZDRAVIL D D NOVO | 2009-09-23 | — | — | CN | disclosed |
| CN-100482645-C | Methods of reversing and preventing cardiovascular pathologies | ATHEROGENICS INC (US) | 2009-04-29 | — | — | CN | disclosed |
| CN-101420991-A | Polymer compositions and methods for their use | ANGIOTECH INT AG (CH) | 2009-04-29 | — | — | CN | disclosed |
| EP-1470258-A1 | COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS | TFL Ledertechnik GmbH (DE) | 2004-10-27 | — | — | EP | disclosed |
| CN-1537098-A | Crystalline forms VI and VII of atorvastatin calcium | ʵ | 2004-10-13 | — | — | CN | disclosed |
| CN-1157374-C | Process for preparation of amorphous atorvastatin calcium | ����˹ҩ�﹤�� | 2004-07-14 | — | — | CN | disclosed |
| WO-2003064707-A1 | COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS | TFL LEDERTECHNIK GMBH (DE) | 2003-08-07 | — | — | WO | disclosed |
| CN-1379760-A | Process for the preparation of amorphous atorvastatin calcium | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2002-11-13 | — | — | CN | disclosed |
| CN-1087288-C | Crystalline [R-(R',R')]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(5-methylethyl)-3-phenyl-4-(phenylamino) carbonyl]-1H-pyrole-1-heptanoic acid hemi calcium salt (atorvastatin) | WARNER LAMBERT CO (US) | 2002-07-10 | — | — | CN | disclosed |
| CN-1130188-A | Salt of phosphonocarboxyl sulfonate zoomaricoene synthetic inhibitor and method | BRISTOL MYERS SKIP CO (US) | 1996-09-04 | — | — | CN | disclosed |
| CN-1089614-A | Alpha-phosphonosulfonate squalene synthetase inhibitors and method | SQUIBB & SONS INC (US) | 1994-07-20 | — | — | CN | disclosed |