Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3026480 | 0.73 | CYP2C9 (0.33) | — | |
| SCHEMBL4297377 | 0.69 | — | — | |
| SCHEMBL10172376 | 0.69 | — | — | |
| SCHEMBL9954953 | 0.69 | — | — | |
| SCHEMBL23323886 | 0.69 | ACE (0.38) | CA12CA1CA9KDM4EMAPT | |
| SCHEMBL26179009 | 0.68 | — | — | |
| SCHEMBL22449493 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL11129917 | 0.68 | — | — | |
| SCHEMBL26731701 | 0.65 | GABRR1 (0.41) | — | |
| SCHEMBL28985643 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513538-A4 | NOVEL METHODS FOR THE DELIVERY OF POLYNUCLEOTIDES TO CELLS | MIRUS BIO CORP (US) | 2007-08-22 | — | — | EP | disclosed |
| EP-1513538-A2 | NOVEL METHODS FOR THE DELIVERY OF POLYNUCLEOTIDES TO CELLS | Mirus Corporation (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20030235916-A1 | Novel methods for the delivery of polynucleotides to cells | ROCHE MADISON INC. | 2003-12-25 | — | — | US | disclosed |
| WO-2003106636-A2 | NOVEL METHODS FOR THE DELIVERY OF POLYNUCLEOTIDES TO CELLS | MIRUS CORPORATION (US) | 2003-12-24 | — | — | WO | disclosed |