Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 3/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520453 | 0.90 | ALDH1A1 (0.49) | ALDH1A1HPGDCYP1A2GAAKMT2A | |
| SCHEMBL2887319 | 0.88 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP1A2GAAKMT2A | |
| SCHEMBL2887460 | 0.84 | ALDH1A1 (0.55) | ALDH1A1HPGDCYP1A2KMT2AHSD17B10 | |
| SCHEMBL5520454 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HPGDCYP1A2GAAKMT2A | |
| SCHEMBL5527718 | 0.80 | SMN1; SMN2 (0.36) | ALDH1A1HPGDCYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL5525320 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HPGDCYP1A2GAAKMT2A | |
| SCHEMBL5528018 | 0.79 | PTPN11 (0.52) | ALDH1A1HPGDGAAHSD17B10LMNA | |
| SCHEMBL1921091 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HPGDCYP1A2GAAKMT2A | |
| SCHEMBL5520493 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10LMNANPC1 | |
| SCHEMBL5527731 | 0.78 | CDC7 (0.47) | ALDH1A1HPGDGAAKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | ALDH1A1 2042/4885HPGD 563/4885CYP1A2 1304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.