SCHEMBL5525877

SCHEMBL5525877

Cc1cc(NC(=O)C(C)(C)NC(=O)Oc2ccc(Cl)s2)ccc1N1CCOCC1=O

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4466805 0.86 F10 (1.00) F10
SCHEMBL5265784 0.86 F10 (0.59) F10
SCHEMBL5181470 0.86 F10 (0.59) F10
SCHEMBL5531632 0.86 F10 (0.56) F10
SCHEMBL4465206 0.84 F10 (0.67) F10
SCHEMBL5567351 0.81 F10 (0.50) F10
SCHEMBL4000970 0.79 F10 (0.66) F10
SCHEMBL4460040 0.79 F10 (0.85) F10
SCHEMBL4459997 0.79 F10 (0.78) F10
SCHEMBL4467794 0.79 F10 (0.78) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1747217-A1 NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS Boehringer Ingelheim International GmbH (DE) 2007-01-31 EP disclosed
WO-2005111029-A1 NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-11-24 WO disclosed