SCHEMBL5526175

SCHEMBL5526175

CC(C)(C)NC(=O)c1cc(-c2ccc(CO)cn2)n(-c2cccnc2)n1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 5/20 0.54
CNR2 P34972 5/20 0.54
MARS1 P56192 3/20 0.43
FYN P06241 3/20 0.40
SLC16A3 O15427 1/20 0.38
SLC16A1 P53985 1/20 0.38
KDM4E B2RXH2 2/20 0.37
DHODH Q02127 2/20 0.37
CACNA1G O43497 1/20 0.36
CACNA1H O95180 1/20 0.36
SMO Q99835 1/20 0.35
TP53 P04637 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5525714 0.91 CNR1 (0.51) CNR1CNR2MARS1SLC16A3SLC16A1
Hydrochloric Acid SCHEMBL5520798 0.91 CNR1 (0.50) CNR1CNR2MARS1SLC16A3SLC16A1
SCHEMBL5526193 0.91 CNR1 (0.50) CNR1CNR2MARS1SLC16A3SLC16A1
SCHEMBL5525413 0.89 CNR1 (0.48) CNR1CNR2MARS1KDM4EDHODH
SCHEMBL5526417 0.89 CNR1 (0.48) CNR1CNR2MARS1KDM4EDHODH
SCHEMBL5525706 0.88 CNR1 (0.48) CNR1CNR2MARS1SLC16A3SLC16A1
SCHEMBL5526762 0.87 CNR1 (0.47) CNR1CNR2MARS1KDM4EDHODH
SCHEMBL5526640 0.87 CNR1 (0.47) CNR1CNR2MARS1SLC16A3SLC16A1
SCHEMBL14416559 0.87 CNR1 (0.47) CNR1CNR2MARS1SLC16A3SLC16A1
SCHEMBL5522031 0.87 CNR1 (0.52) CNR1CNR2MARS1FYNSLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070219210-A1 Amidopyrazole Derivative DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-09-20 US disclosed
US-20070219210-A1 Amidopyrazole Derivative DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-09-20 US disclosed
US-20070219210-A1 Amidopyrazole Derivative DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-09-20 US disclosed
EP-1698626-A1 AMIDOPYRAZOLE DERIVATIVE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219210-A1 Amidopyrazole Derivative PTGER1, PTGS1, PTGER2 CNR1 76/4885CNR2 43/4885MARS1 2982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.