Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | F13A1 | P00488 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | CA4 | P22748 | 2/20 | 0.62 |
| ▸ | CA6 | P23280 | 2/20 | 0.62 |
| ▸ | CA5A | P35218 | 2/20 | 0.62 |
| ▸ | THPO | P40225 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5533115 | 1.00 | DNM1 (0.65) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL17541834 | 1.00 | DNM1 (0.65) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL5532943 | 1.00 | DNM1 (0.65) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5540296 | 0.98 | DNM1 (0.67) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5540183 | 0.98 | DNM1 (0.67) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL21799586 | 0.97 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL21799687 | 0.97 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL21799606 | 0.97 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL21799816 | 0.97 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL21799968 | 0.97 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789708-B1 | MULTIFUNCTIONAL MOLECULAR COMPLEXES FOR GENE TRANSFER TO CELLS | WYETH CORP (US) | 2004-11-03 | — | — | EP | claimed |
| US-7202227-B2 | Multifunctional molecular complexes for gene transfer to cells | WYETH (US) | 2007-04-10 | — | — | US | disclosed |
| US-20050239204-A1 | Multifunctional molecular complexes for gene transfer to cells | WYETH (US) | 2005-10-27 | — | — | US | disclosed |
| EP-0789708-B1 | MULTIFUNCTIONAL MOLECULAR COMPLEXES FOR GENE TRANSFER TO CELLS | WYETH CORP (US) | 2004-11-03 | — | — | EP | disclosed |
| US-20040214328-A9 | Multifunctional molecular complexes for gene transfer to cells | AMERICAN HOME PRODUCTS CORPORATION (US) | 2004-10-28 | — | — | US | disclosed |
| US-20020155607-A1 | Multifunctional molecular complexes for gene transfer to cells | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-10-24 | — | — | US | disclosed |
| US-6379965-B1 | NUCLEIC ACID NONCOVALENTLY ASSOCIATED WITH A POLYAMINE COMPOUND THAT IS COVALENTLY ATTACHED TO AN ENDOSOME DISRUPTING AGENT SUCH AS CHOLIC ACID; NONVIRAL VECTORS | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0789708-A4 | MULTIFUNCTIONAL MOLECULAR COMPLEXES FOR GENE TRANSFER TO CELLS | APOLLON INC (US) | 1999-12-29 | — | — | EP | disclosed |
| US-5837533-A | CATIONIC AMINE COMPOUND TRANSFER MOIETY AND NUCLEIC ACID FOR MEMBRANES FOR IMMUNOLOGY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-11-17 | — | — | US | disclosed |
| EP-0789708-A1 | MULTIFUNCTIONAL MOLECULAR COMPLEXES FOR GENE TRANSFER TO CELLS | APOLLON, INC. (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996010038-A1 | MULTIFUNCTIONAL MOLECULAR COMPLEXES FOR GENE TRANSFER TO CELLS | APOLLON, INC. (US) | 1996-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214328-A9 | Multifunctional molecular complexes for gene transfer to cells | SNRPE, TARBP1, HNRNPH3 | DNM1 249/4885TSHR 1967/4885ALDH1A1 4586/4885 |
| US-20020155607-A1 | Multifunctional molecular complexes for gene transfer to cells | SNRPE, TARBP1, HNRNPH3 | DNM1 249/4885TSHR 1967/4885ALDH1A1 4586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.