Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.49 |
| ▸ | PTAFR | P25105 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3562026 | 0.95 | ALDH1A1 (0.90) | ALDH1A1KDM4EHRH3MAPTCRHBP | |
| SCHEMBL13650840 | 0.87 | ALDH1A1 (0.77) | ALDH1A1KDM4EHRH3MAPTCRHBP | |
| SCHEMBL6705715 | 0.87 | ALDH1A1 (0.77) | ALDH1A1KDM4EHRH3MAPTCRHBP | |
| SCHEMBL1936341 | 0.87 | ALDH1A1 (0.77) | ALDH1A1KDM4EHRH3MAPTCRHBP | |
| Hydrochloric Acid SCHEMBL1935125 | 0.85 | ALDH1A1 (0.74) | ALDH1A1KDM4EHRH3MAPTCRHBP | |
| SCHEMBL16254918 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KDM4EHRH3MAPTCRHBP | |
| SCHEMBL21163109 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KDM4EHRH3MAPTCRHBP | |
| SCHEMBL3225452 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KDM4EHRH3MAPTCRHBP | |
| SCHEMBL6694425 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KDM4EHRH3MAPTCRHBP | |
| SCHEMBL18779478 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KDM4EHRH3MAPTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213339-A1 | Quinolone Carboxylic Acid Derivatives for Treatment of Hyperproliferative Conditions | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213339-A1 | Quinolone Carboxylic Acid Derivatives for Treatment of Hyperproliferative Conditions | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213339-A1 | Quinolone Carboxylic Acid Derivatives for Treatment of Hyperproliferative Conditions | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-09-13 | — | — | US | disclosed |
| EP-1732897-A1 | QUINOLONE CARBOXYLIC ACID DERIVATIVES FOR TREATMENT OF HYPERPROLIFERATIVE CONDITIONS | Bayer Pharmaceuticals Corporation (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005097752-A1 | QUINOLONE CARBOXYLIC ACID DERIVATIVES FOR TREATMENT OF HYPERPROLIFERATIVE CONDITIONS | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213339-A1 | Quinolone Carboxylic Acid Derivatives for Treatment of Hyperproliferative Conditions | TP53, RB1, HRAS | ALDH1A1 272/4885KDM4E 2571/4885HRH3 494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.