Adenine

Adenine

SCHEMBL55284

CC(=O)c1cccnc1.Nc1ncnc2nc[nH]c12

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 2/20 0.54
PI4K2B Q8TCG2 2/20 0.54
PI4K2A Q9BTU6 2/20 0.54
PI4KB Q9UBF8 2/20 0.54
LMNA P02545 2/20 0.54
DRD3 P35462 1/20 0.54
XDH P47989 1/20 0.54
LRRK2 Q5S007 1/20 0.54
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
BRD4 O60885 2/20 0.43
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
EGFR P00533 1/20 0.41
SRC P12931 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenine SCHEMBL6810324 0.95 PI4KA (0.49) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL6480078 0.95 PI4KA (0.49) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL9274699 0.89 PI4KA (0.52) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL2564210 0.89 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL22748487 0.89 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL15700 0.89 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL1271542 0.89 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL23531102 0.88 PI4KA (0.54) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL11807683 0.88 PI4KA (0.54) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL7712108 0.88 PI4KA (0.54) PI4KAPI4K2BPI4K2API4KBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 365 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118033103-A Carbon dioxide detection reagent and/or kit 北京安图生物工程有限公司 2024-05-14 CN claimed
CN-114354524-A Stable liquid detection kit 北京九强生物技术股份有限公司 2022-04-15 CN claimed
CN-111996234-A Serum carbon dioxide detection kit and preparation method thereof 安徽伊普诺康生物技术股份有限公司 2020-11-27 CN claimed
CN-111893162-A Carbon dioxide enzyme method determination kit 武汉生之源生物科技股份有限公司 2020-11-06 CN claimed
CN-111575339-A 1, 5-anhydroglucitol enzymatic quantitative method and reagent therefor 王学忠 2020-08-25 CN claimed
WO-2019022469-A1 USE OF NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (NADPH) OR DERIVATIVE THEREOF AS BETA-LACTAMASE INHIBITOR 전북대학교산학협력단 2019-01-31 WO claimed
US-8690857-B2 Alleviate back pain with lactic acid inhibitors ALEEVA MEDICAL INC. (US) 2014-04-08 US claimed
CN-103601780-A Synthetic method of 3-acetylpyridine adenine dinucleotide BEIJING LEADMAN BIOCHEMISTRY CO LTD 2014-02-26 CN claimed
US-20130071871-A1 ENZYMATIC DETERMINATION OF LITHIUM IONS USING PHOSPHOGLUCOMUTASE SPECIALTY ASSAYS, INC. (US) 2013-03-21 US claimed
US-20120022425-A1 Alleviate back pain with lactic acid inhibitors YEUNG JEFFREY ERIC (US) 2012-01-26 US claimed
WO-2009135035-A1 ENZYMATIC DETERMINATION OF POTASSIUM IONS USING STABLE NAD(P)H ANALOGS. SPECIALTY ASSAYS, INC. (US) 2009-11-05 WO claimed
US-6974665-B2 In situ screening to optimize variables in organic reactions UNIVERSITY OF NEBRASKA (US) 2005-12-13 US claimed
US-20030148257-A1 In situ screening to optimize variables in organic reactions UNIVERSITY OF NEBRASKA (US) 2003-08-07 US claimed
US-6339073-B1 Uses of nicotinamide adenine dinucleotide and its derivatives for treatment of malignant and infectious diseases OXIGENE, INC. 2002-01-15 US claimed
WO-1997024141-A1 MONOCLONAL ANTIBODIES AND IMMUNO-CAPTURE METHOD FOR QUANTITATION AND SPECIATION OF MALARIA PARASITES PIPER ROBERT C (US) 1997-07-10 WO claimed
WO-1993021330-A1 HUMAN GLUTAMINE:FRUCTOSE-6-PHOSPHATE AMINO-TRANSFERASE ZYMOGENETICS, INC. (US) 1993-10-28 WO claimed
US-5124141-A METHOD FOR DIAGNOSING MALARIA FLOW INCORPORATED (US) 1992-06-23 US claimed
WO-1991019974-A1 METHOD AND COMPOSITION FOR DIAGNOSING MALARIA FLOW, INC. (US) 1991-12-26 WO claimed
EP-2068918-B2 VACCINE COMPOSITION CONTAINING SYNTHETIC ADJUVANT ACCESS TO ADVANCED HEALTH INST (US) 2024-07-03 EP disclosed
US-4166763-A BY MEASURING AMOUNT OF HYDROGEN PEROXIDE PRODUCED EASTMAN KODAK COMPANY (US) 1979-09-04 US disclosed