Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | RPA1 | P27694 | 3/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5525576 | 0.89 | NTRK1 (0.33) | SMOMLLT1NTRK1RPA1CSF1R | |
| SCHEMBL5525372 | 0.89 | MALT1 (0.35) | RPA1CSF1RNAMPTP2RX7CCNE1 | |
| SCHEMBL5525748 | 0.88 | SMO (0.37) | SMOMLLT1NTRK1RPA1CYP11B1 | |
| SCHEMBL5524300 | 0.87 | CYP11B1 (0.37) | SMOMLLT1CSF1RCYP11B1CCNE1 | |
| SCHEMBL5521080 | 0.87 | MLLT1 (0.49) | SMOMLLT1NTRK1CSF1RADORA2A | |
| SCHEMBL5525538 | 0.84 | OXTR (0.36) | SMORPA1CYP11B1P2RX7MALT1 | |
| SCHEMBL14416571 | 0.83 | RPA1 (0.36) | SMORPA1CSF1RP2RX7CCNE1 | |
| SCHEMBL5148813 | 0.82 | RPA1 (0.47) | SMORPA1MALT1 | |
| SCHEMBL5521163 | 0.82 | OXTR (0.45) | SMORPA1MALT1ADORA2AOXTR | |
| SCHEMBL5524209 | 0.82 | PIK3CA (0.35) | RPA1NAMPTP2RX7CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1698626-A1 | AMIDOPYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | PTGER1, PTGS1, PTGER2 | SMO 2054/4885MLLT1 1463/4885NTRK1 3841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.