Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 12/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16112894 | 0.83 | ANO1 (0.47) | ANO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3541223 | 0.82 | ANO1 (0.48) | ANO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5315105 | 0.81 | ANO1 (0.46) | ANO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3534077 | 0.79 | ANO1 (0.45) | ANO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5522655 | 0.79 | CYP3A4 (0.44) | — | |
| SCHEMBL16113566 | 0.78 | ANO1 (0.45) | ANO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3543307 | 0.77 | KDM4E (0.65) | ANO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1919537 | 0.77 | ANO1 (0.43) | ANO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3544726 | 0.77 | ANO1 (0.43) | ANO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2856691 | 0.76 | ANO1 (0.42) | ANO1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265152-B2 | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases | VIROPHARMA INCORPORATED (US) | 2007-09-04 | — | — | US | claimed |