Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 3/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529104 | 0.87 | CNR1 (0.51) | MARS1CNR1CNR2DHODHMALT1 | |
| SCHEMBL5978720 | 0.86 | CNR2 (0.65) | MARS1NTRK1CNR1CNR2MALT1 | |
| SCHEMBL5524832 | 0.85 | CNR1 (0.54) | MARS1NTRK1CNR1CNR2DHODH | |
| SCHEMBL4932725 | 0.82 | MARS1 (0.64) | MARS1MEN1KMT2A | |
| SCHEMBL5528409 | 0.81 | CNR1 (0.45) | MARS1NTRK1CNR1CNR2NTRK3 | |
| SCHEMBL5521994 | 0.81 | CNR1 (0.45) | MARS1NTRK1CNR1CNR2NTRK3 | |
| SCHEMBL4927109 | 0.80 | KMT2A (0.52) | MARS1MEN1KMT2A | |
| SCHEMBL5530134 | 0.79 | CNR1 (0.50) | MARS1NTRK1CNR1CNR2MALT1 | |
| SCHEMBL5522084 | 0.77 | CNR1 (0.52) | MARS1CNR1CNR2DHODHMALT1 | |
| SCHEMBL5522031 | 0.77 | CNR1 (0.52) | MARS1CNR1CNR2MALT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | PTGER1, PTGS1, PTGER2 | MARS1 2982/4885NTRK1 3841/4885CNR1 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.