Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 4/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.47 |
| ▸ | LYN | P07948 | 3/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.39 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5525540 | 0.89 | PRKCQ (0.47) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL5521082 | 0.81 | PRKCQ (0.59) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL28771753 | 0.81 | PRKCQ (0.72) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL5524664 | 0.74 | PRKCQ (0.61) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL5530012 | 0.73 | PRKCQ (0.69) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL27739652 | 0.71 | PRKCQ (0.70) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL20031290 | 0.69 | PRKCI (0.61) | ALDH1A1 | |
| SCHEMBL4941352 | 0.68 | PRKCQ (0.60) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL5523867 | 0.66 | PRKCQ (0.55) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL5517780 | 0.66 | EGFR (0.62) | PRKCQPRKCDLYNEGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070082880-A1 | Thieno [2,3-B] pyridine-5-carbonitriles as protein kinase inhibitors | WYETH | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082880-A1 | Thieno [2,3-B] pyridine-5-carbonitriles as protein kinase inhibitors | MAP4K2, CNKSR1, MAP3K1 | PRKCQ 286/4885PRKCD 356/4885LYN 398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.