Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.59 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.59 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.56 |
| ▸ | PREP | P48147 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529957 | 0.87 | DPP4 (0.59) | DPP4DPP8DPP7PREP | |
| SCHEMBL6692174 | 0.79 | DPP4 (0.58) | DPP4DPP8DPP7PREP | |
| SCHEMBL713741 | 0.77 | DPP4 (0.64) | DPP4DPP8DPP7PREP | |
| SCHEMBL719969 | 0.77 | DPP4 (0.64) | DPP4DPP8DPP7PREP | |
| SCHEMBL3554544 | 0.74 | DPP4 (1.00) | DPP4DPP8DPP7PREP | |
| SCHEMBL3554547 | 0.74 | DPP4 (1.00) | DPP4DPP8DPP7PREP | |
| SCHEMBL3546674 | 0.73 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL3546678 | 0.73 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL14392633 | 0.73 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL6685692 | 0.73 | DPP4 (0.46) | DPP4DPP8DPP7PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1760076-A1 | FAP Inhibitors | FERRING B.V. (NL) | 2007-03-07 | — | — | EP | claimed |
| EP-1760076-A1 | FAP Inhibitors | FERRING B.V. (NL) | 2007-03-07 | — | — | EP | disclosed |