Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.47 |
| ▸ | RELA | Q04206 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16885031 | 0.99 | THRB (0.61) | THRBTDP1LMNANPC1CYP3A4 | |
| SCHEMBL5517403 | 0.97 | THRB (0.62) | THRBTDP1LMNANPC1CYP3A4 | |
| SCHEMBL1945995 | 0.96 | THRB (0.65) | THRBTDP1LMNANPC1CYP3A4 | |
| SCHEMBL19354406 | 0.96 | THRB (0.65) | THRBTDP1LMNANPC1CYP3A4 | |
| SCHEMBL24599284 | 0.95 | THRB (0.63) | THRBTDP1LMNANPC1CYP3A4 | |
| SCHEMBL24599283 | 0.95 | THRB (0.63) | THRBTDP1LMNANPC1CYP3A4 | |
| SCHEMBL16674157 | 0.93 | THRB (0.55) | THRBTDP1LMNANPC1CYP3A4 | |
| SCHEMBL13220816 | 0.93 | THRB (0.55) | THRBTDP1LMNANPC1CYP3A4 | |
| SCHEMBL12794252 | 0.93 | THRB (0.55) | THRBTDP1LMNANPC1CYP3A4 | |
| SCHEMBL450098 | 0.93 | THRB (0.55) | THRBTDP1LMNANPC1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007083848-A1 | COMPOSITION, RETARDATION PLATE, LIQUID-CRYSTAL DISPLAY DEVICE, AND METHOD FOR PRODUCING RETARDATION PLATE | FUJIFILM CORPORATION (JP) | 2007-07-26 | — | — | WO | disclosed |