Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.64 |
| ▸ | DDO | Q99489 | 2/20 | 0.64 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165132 | 0.81 | UCHL1 (0.49) | PARP1KDM4ETDP1PBRM1GAA | |
| SCHEMBL30189206 | 0.80 | FLT3 (0.60) | DAODDOKDM4ETDP1GAA | |
| SCHEMBL3417091 | 0.80 | FLT3 (0.60) | DAODDOKDM4ETDP1GAA | |
| SCHEMBL5862683 | 0.79 | KDM4E (0.56) | DAODDOKDM4EGAAALDH1A1 | |
| SCHEMBL3363456 | 0.78 | DAO (1.00) | DAODDOKDM4EALDH1A1FLT3 | |
| SCHEMBL9286942 | 0.77 | PARP1 (0.46) | DAODDOPARP1KDM4ETDP1 | |
| SCHEMBL27492839 | 0.77 | PARP1 (0.46) | DAODDOPARP1KDM4ETDP1 | |
| SCHEMBL4426955 | 0.75 | DAO (0.56) | DAODDOPARP1KDM4EALDH1A1 | |
| SCHEMBL3168872 | 0.75 | PARP1 (0.43) | DAODDOPARP1KDM4ETDP1 | |
| SCHEMBL12970533 | 0.75 | DAO (0.65) | DAODDOPARP1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1338599-B1 | Optically pure analogues of Camptothecin | SOD CONSEILS RECH APPLIC (FR) | 2007-02-14 | — | — | EP | disclosed |
| EP-1338599-A1 | Optically pure analogues of Camptothecin | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2003-08-27 | — | — | EP | disclosed |
| EP-1165565-B1 | OPTICALLY PURE CAMPTOTHECIN ANALOGUES | SOD CONSEILS RECH APPLIC (FR) | 2003-06-04 | — | — | EP | disclosed |
| EP-1165565-A1 | OPTICALLY PURE CAMPTOTHECIN ANALOGUES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000050427-A1 | OPTICALLY PURE CAMPTOTHECIN ANALOGUES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-08-31 | — | — | WO | disclosed |