Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | CKS1B | P61024 | 13/20 | 0.46 |
| ▸ | SKP1 | P63208 | 13/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 13/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.41 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | YES1 | P07947 | 1/20 | 0.41 |
| ▸ | HCK | P08631 | 1/20 | 0.41 |
| ▸ | FGR | P09769 | 1/20 | 0.41 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.41 |
| ▸ | GRK4 | P32298 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14545578 | 0.83 | CNR1 (0.62) | CNR1CKS1BSKP1SKP2 | |
| SCHEMBL4690127 | 0.82 | CNR1 (0.52) | CNR1CKS1BSKP1SKP2 | |
| SCHEMBL4695724 | 0.82 | KMT2A (0.41) | CKS1BSKP1SKP2PIK3CDPIK3R1 | |
| SCHEMBL4811669 | 0.81 | CNR1 (0.42) | CNR1CKS1BSKP1SKP2 | |
| SCHEMBL3554487 | 0.79 | CHRM4 (0.51) | — | |
| SCHEMBL5527891 | 0.77 | SLC6A7 (0.41) | — | |
| SCHEMBL5530911 | 0.77 | CKS1B (0.68) | CNR1CKS1BSKP1SKP2 | |
| SCHEMBL3787774 | 0.73 | CHRM4 (0.49) | PIK3CDPIK3R1PIK3C2BAURKAMAP4K4 | |
| SCHEMBL25264632 | 0.73 | CHRM4 (0.48) | — | |
| SCHEMBL4508825 | 0.72 | GRM4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078135-A1 | Substituted heteroaryl CB1 antagonists | NEUROGEN CORPORATION (US) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078135-A1 | Substituted heteroaryl CB1 antagonists | CNR1, CNR2, OPRL1 | CNR1 1/4885CKS1B 1836/4885SKP1 3576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.