Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4823560 | 0.74 | CYP1A2 (0.48) | LMNACYP2D6CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL15262579 | 0.70 | SMN1; SMN2 (0.38) | CYP2C9CYP2C19SMN1; SMN2HIF1AFDPS | |
| SCHEMBL8515125 | 0.70 | SMN1; SMN2 (0.38) | CYP2C9CYP2C19SMN1; SMN2HIF1AFDPS | |
| SCHEMBL8874556 | 0.69 | KIF11 (0.37) | CYP2D6CYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL2346144 | 0.69 | SMN1; SMN2 (0.37) | ALDH1A1CYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL3443952 | 0.69 | CYP2C9 (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL12265952 | 0.66 | SMN1; SMN2 (0.45) | LMNACYP2D6ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8874125 | 0.66 | CPA1 (0.36) | LMNAALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL4816699 | 0.66 | SMN1; SMN2 (0.41) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL14896221 | 0.65 | CYP1A2 (0.32) | CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748993-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005116000-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2005-12-08 | — | — | WO | disclosed |