Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | ESRRG | P62508 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1825311 | 0.84 | ESR1 (0.53) | ESR1ESR2HPGDTSHRCYP3A4 | |
| SCHEMBL1123840 | 0.80 | ESR1 (0.57) | ESR1ESR2HPGDTSHRCYP3A4 | |
| SCHEMBL1123616 | 0.78 | ESR1 (0.53) | ESR1ESR2HPGDTSHRCYP3A4 | |
| SCHEMBL5179757 | 0.77 | ESR1 (0.44) | ESR1ESR2HPGDTSHRCYP3A4 | |
| SCHEMBL11143073 | 0.77 | ESR1 (0.44) | ESR1ESR2HPGDTSHRCYP3A4 | |
| Bisphenol A SCHEMBL9247296 | 0.76 | ESR1 (0.52) | ESR1ESR2HPGDTSHRCYP3A4 | |
| Bisphenol A SCHEMBL5179752 | 0.76 | ESR1 (0.52) | ESR1ESR2HPGDTSHRCYP3A4 | |
| SCHEMBL5025771 | 0.75 | ESR2 (0.59) | ESR1ESR2HPGDTSHRCYP3A4 | |
| SCHEMBL3807953 | 0.75 | ESR1 (0.42) | ESR1ESR2HPGDTSHRCYP3A4 | |
| SCHEMBL824168 | 0.74 | CA12 (0.49) | HPGDTSHRARALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070255005-A1 | Process for Producing Curable Resin Composition | KANEKA BELGIUM N.V. (BE) | 2007-11-01 | — | — | US | disclosed |
| EP-1767584-A1 | PROCESS FOR PRODUCING CURABLE RESIN COMPOSITION | Kaneka Corporation (JP) | 2007-03-28 | — | — | EP | disclosed |