SCHEMBL1825311

SCHEMBL1825311

C=CCOc1ccc(C(C)(C)c2ccc(O)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.53
ESR2 Q92731 3/20 0.53
HPGD P15428 3/20 0.53
TSHR P16473 3/20 0.53
CYP3A4 P08684 2/20 0.53
AR P10275 1/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A4 P31645 1/20 0.53
HTR6 P50406 1/20 0.53
ESRRG P62508 1/20 0.53
SLC6A3 Q01959 1/20 0.53
HSD17B10 Q99714 1/20 0.53
ALDH1A1 P00352 5/20 0.47
GAA P10253 5/20 0.46
MGAM O43451 3/20 0.46
SI P14410 3/20 0.46
MGAM2 Q2M2H8 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
KDM4E B2RXH2 1/20 0.45
MAPT P10636 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL824168 0.91 CA12 (0.49) HPGDTSHRARALDH1A1GAA
SCHEMBL4570343 0.91 CA12 (0.49) HPGDTSHRARALDH1A1GAA
SCHEMBL15869178 0.86 CA12 (0.45) HPGDTSHRARALDH1A1GAA
SCHEMBL261038 0.86 CA12 (0.53) ESR1ESR2HPGDSLC6A2SLC6A3
SCHEMBL11121843 0.85 SMN1; SMN2 (0.57) ESR1ESR2CYP3A4ALDH1A1GAA
SCHEMBL12370719 0.85 ALDH1A1 (0.51) HPGDTSHRALDH1A1GAASMN1; SMN2
SCHEMBL20233954 0.85 MAPT (0.55) HPGDTSHRALDH1A1GAASMN1; SMN2
SCHEMBL5531121 0.84 ESR1 (0.50) ESR1ESR2HPGDTSHRCYP3A4
SCHEMBL12168699 0.83 TP53 (0.47) HPGDTSHRARALDH1A1GAA
SCHEMBL18615415 0.83 ALDH1A1 (0.50) CYP3A4ARALDH1A1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813910-A MQ silicon resin and preparation method and application thereof 陕西沦柳仑新材料科技有限公司 2023-09-29 CN disclosed
US-10428176-B2 Thermosetting alkoxysilyl compound having two or more alkoxysilyl groups, composition and cured product comprising same, use thereof, and method for preparing alkoxysilyl compound KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2019-10-01 US disclosed
US-20180155370-A1 THERMOSETTING ALKOXYSILYL COMPOUND HAVING TWO OR MORE ALKOXYSILYL GROUPS, COMPOSITION AND CURED PRODUCT COMPRISING SAME, USE THEREOF, AND METHOD FOR PREPARING ALKOXYSILYL COMPOUND KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-06-07 US disclosed
US-20180155370-A1 THERMOSETTING ALKOXYSILYL COMPOUND HAVING TWO OR MORE ALKOXYSILYL GROUPS, COMPOSITION AND CURED PRODUCT COMPRISING SAME, USE THEREOF, AND METHOD FOR PREPARING ALKOXYSILYL COMPOUND KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-06-07 US disclosed
US-9896535-B2 Epoxy compound having alkoxysilyl group, method of preparing the same, composition and cured product comprising the same, and uses thereof KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-02-20 US disclosed
US-9896535-B2 Epoxy compound having alkoxysilyl group, method of preparing the same, composition and cured product comprising the same, and uses thereof KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-02-20 US disclosed
US-9896535-B2 Epoxy compound having alkoxysilyl group, method of preparing the same, composition and cured product comprising the same, and uses thereof KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-02-20 US disclosed
EP-2767535-B1 EPOXY COMPOUND HAVING ALKOXYSILYL GROUP, METHOD FOR PREPARING SAME, COMPOSITION AND CURED MATERIAL COMPRISING SAME, AND USAGE THEREOF KOREA IND TECH INST (KR) 2016-08-24 EP disclosed
EP-2767535-B1 EPOXY COMPOUND HAVING ALKOXYSILYL GROUP, METHOD FOR PREPARING SAME, COMPOSITION AND CURED MATERIAL COMPRISING SAME, AND USAGE THEREOF KOREA IND TECH INST (KR) 2016-08-24 EP disclosed
US-20160229948-A1 EPOXY COMPOUND HAVING ALKOXYSILYL GROUP, METHOD OF PREPARING THE SAME, COMPOSITION AND CURED PRODUCT COMPRISING THE SAME, AND USES THEREOF KOREA IND TECH INST (KR) 2016-08-11 US disclosed
US-5266650-A Shaping and curing for hoses and o-rings MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-30 US disclosed
US-5262490-A Sulfonium, phosphonium and ammonium accelerators MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-16 US disclosed
EP-0566692-A1 CURING FLUOROCARBON ELASTOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-10-27 EP disclosed
WO-1992012199-A1 CURING FLUOROCARBON ELASTOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-07-23 WO disclosed
EP-0466340-A2 Curing fluorocarbon elastomers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-15 EP disclosed
EP-0432911-A1 Polymer blend composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-06-19 EP disclosed
EP-0404411-A1 Fluoroelastomer composition with improved bonding properties MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-12-27 EP disclosed
US-4912171-A Blend of addition polymer, polyhydroxy compound, organo-onium compound and acid acceptor MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-03-27 US disclosed
US-4882390-A AND POLYHYDROXY COMPOUND MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-11-21 US disclosed
EP-0335705-A1 Fluoroelastomer composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10428176-B2 Thermosetting alkoxysilyl compound having two or more alkoxysilyl groups, composition and cured product comprising same, use thereof, and method for preparing alkoxysilyl compound PIEZO1, FTO, ESD ESR1 1463/4885ESR2 2787/4885HPGD 4507/4885
US-20180155370-A1 THERMOSETTING ALKOXYSILYL COMPOUND HAVING TWO OR MORE ALKOXYSILYL GROUPS, COMPOSITION AND CURED PRODUCT COMPRISING SAME, USE THEREOF, AND METHOD FOR PREPARING ALKOXYSILYL COMPOUND PIEZO1, FTO, ESD ESR1 1463/4885ESR2 2787/4885HPGD 4507/4885
US-20160229948-A1 EPOXY COMPOUND HAVING ALKOXYSILYL GROUP, METHOD OF PREPARING THE SAME, COMPOSITION AND CURED PRODUCT COMPRISING THE SAME, AND USES THEREOF PFAS, FAR1, ELOVL1 ESR1 67/4885ESR2 177/4885HPGD 2962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.