Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 10/20 | 0.75 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.75 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.75 |
| ▸ | CA1 | P00915 | 3/20 | 0.72 |
| ▸ | CA2 | P00918 | 3/20 | 0.72 |
| ▸ | CA9 | Q16790 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | ESR1 | P03372 | 2/20 | 0.72 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.72 |
| ▸ | CA4 | P22748 | 1/20 | 0.72 |
| ▸ | CA6 | P23280 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622302 | 1.00 | STS (0.75) | STSABCC4CYP2C9ABCC1SLCO1B1 | |
| SCHEMBL8214105 | 0.88 | STS (0.77) | STSABCC4CYP2C9ABCC1SLCO1B1 | |
| SCHEMBL6140924 | 0.88 | STS (0.77) | STSABCC4CYP2C9ABCC1SLCO1B1 | |
| SCHEMBL10031986 | 0.87 | STS (0.79) | STSABCC4CYP2C9ABCC1SLCO1B1 | |
| SCHEMBL1784724 | 0.86 | STS (0.78) | STSABCC4CYP2C9ABCC1SLCO1B1 | |
| Estrone Sulfuric Acid SCHEMBL12920398 | 0.86 | STS (1.00) | STSABCC4CYP2C9ABCC1SLCO1B1 | |
| Estrone Sulfuric Acid SCHEMBL29369653 | 0.86 | STS (1.00) | STSABCC4CYP2C9ABCC1SLCO1B1 | |
| Estrone Sulfuric Acid SCHEMBL22846 | 0.86 | STS (1.00) | STSABCC4CYP2C9ABCC1SLCO1B1 | |
| Estrone Sulfuric Acid SCHEMBL14375453 | 0.86 | STS (1.00) | STSABCC4CYP2C9ABCC1SLCO1B1 | |
| Estrone Sulfuric Acid SCHEMBL6530673 | 0.86 | STS (1.00) | STSABCC4CYP2C9ABCC1SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275935-A1 | Estratriene Derivatives | CRYPTOPHARMA PTY LTD (AU) | 2007-11-29 | — | — | US | disclosed |
| EP-1625143-A1 | ESTRATRIENE DERIVATIVES | Cryptopharma Pty Ltd (AU) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004101595-A1 | ESTRATRIENE DERIVATIVES | CRYPTOPHARMA PTY LTD (AU) | 2004-11-25 | — | — | WO | disclosed |
| EP-1169336-A1 | ENT-STEROIDS AS SELECTIVELY ACTIVE ESTROGENS | Schering Aktiengesellschaft (DE) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000063228-A1 | ENT-STEROIDS AS SELECTIVELY ACTIVE ESTROGENS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275935-A1 | Estratriene Derivatives | ESR2, ESRRB, NR3C2 | STS 844/4885ABCC4 3799/4885CYP2C9 1774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.