Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | RPA1 | P27694 | 3/20 | 0.38 |
| ▸ | BCL2 | P10415 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | KLK3 | P07288 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529139 | 0.90 | MALT1 (0.42) | MALT1CHRNA7RPA1BCL2MDM2 | |
| SCHEMBL5527852 | 0.87 | OXTR (0.36) | MALT1CHRNA7OXTRAVPR1A | |
| Hydrochloric Acid SCHEMBL5151848 | 0.86 | MALT1 (0.43) | MALT1CHRNA7RPA1BCL2MDM2 | |
| SCHEMBL14504508 | 0.85 | MALT1 (0.42) | MALT1CHRNA7RPA1BCL2MDM2 | |
| SCHEMBL14504623 | 0.84 | MALT1 (0.43) | MALT1CHRNA7RPA1BCL2MDM2 | |
| SCHEMBL14504646 | 0.84 | MDM2 (0.45) | MALT1CHRNA7RPA1BCL2MDM2 | |
| SCHEMBL5521012 | 0.84 | MALT1 (0.40) | MALT1CHRNA7RPA1BCL2MDM2 | |
| Hydrochloric Acid SCHEMBL5148947 | 0.84 | MDM2 (0.43) | MALT1CHRNA7RPA1BCL2MDM2 | |
| SCHEMBL5152076 | 0.83 | RPA1 (0.44) | MALT1CHRNA7RPA1NFKB1NFKB2 | |
| SCHEMBL6208574 | 0.82 | MDM2 (0.41) | MALT1CHRNA7RPA1BCL2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1698626-A1 | AMIDOPYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | PTGER1, PTGS1, PTGER2 | MALT1 3117/4885CHRNA7 4667/4885RPA1 1661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.