Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529380 | 0.79 | HSP90AA1 (0.43) | MAPK1DCUN1D1HSP90AA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4226477 | 0.79 | HSP90AA1 (0.54) | MAPK1DCUN1D1HSP90AA1USP7ALDH1A1 | |
| SCHEMBL5524404 | 0.76 | PDE7A (0.39) | MAPK1HSP90AA1SMN1; SMN2NPC1GAA | |
| SCHEMBL13903600 | 0.74 | HSP90AA1 (0.49) | MAPK1DCUN1D1HSP90AA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5530138 | 0.71 | ABL1 (0.40) | MAPK1HSP90AA1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6307067 | 0.70 | HSP90AA1 (0.69) | MAPK1HSP90AA1ALDH1A1SMN1; SMN2ADORA2A | |
| SCHEMBL23405305 | 0.69 | MAPK1 (0.41) | MAPK1DCUN1D1HSP90AA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4603390 | 0.69 | TSHR (0.42) | MAPK1DCUN1D1ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL27826457 | 0.69 | MPL (0.45) | MAPK1HSP90AA1SMN1; SMN2NPC1MAPT | |
| SCHEMBL9048605 | 0.68 | MAPK1 (0.36) | MAPK1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208037-A1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | PEES KLAUS-JUERGEN | 2007-09-06 | — | — | US | disclosed |
| US-7230104-B2 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-12 | — | — | US | disclosed |
| CN-1279027-C | Fungicidal 5-phenyl substituted 2- (cyanamido) pyrimidines | BASF AG (DE) | 2006-10-11 | — | — | CN | disclosed |
| US-20050282828-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | PEES KLAUS-JUERGEN | 2005-12-22 | — | — | US | disclosed |
| US-20050282847-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | PEES KLAUS-JUERGEN | 2005-12-22 | — | — | US | disclosed |
| EP-1577312-A1 | Triazolopyrimidine intermediate compounds for fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-21 | — | — | EP | disclosed |
| US-6943252-B2 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-13 | — | — | US | disclosed |
| EP-1289963-B1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | BASF AG (DE) | 2005-08-31 | — | — | EP | disclosed |
| US-20040147744-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | PEES KLAUS-JUERGEN | 2004-07-29 | — | — | US | disclosed |
| US-6632821-B2 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2003-10-14 | — | — | US | disclosed |
| CN-1443174-A | Fungicidal 5-phenyl substituted 2- (cyanamido) pyrimidines | BASF AG (DE) | 2003-09-17 | — | — | CN | disclosed |
| US-20030088096-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147744-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR3, CBR1, NOX5 | MAPK1 1618/4885DCUN1D1 1622/4885HSP90AA1 1002/4885 |
| US-20050282828-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR3, CBR1, CYP3A5 | MAPK1 2611/4885DCUN1D1 2496/4885HSP90AA1 1647/4885 |
| US-20070208037-A1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | CBR3, NOX5, CBR1 | MAPK1 2955/4885DCUN1D1 2483/4885HSP90AA1 1355/4885 |
| US-20030088096-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR1, CBR3, ARSA | MAPK1 1898/4885DCUN1D1 2207/4885HSP90AA1 714/4885 |
| US-20050282847-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR3, NOX5, CBR1 | MAPK1 3068/4885DCUN1D1 2742/4885HSP90AA1 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.