Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4231717 | 0.82 | HSP90AA1 (0.57) | HSP90AA1MAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL5532703 | 0.79 | MAPK1 (0.49) | HSP90AA1MAPK1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL5530138 | 0.78 | ABL1 (0.40) | HSP90AA1MAPK1ALDH1A1MAPTKMT2A | |
| SCHEMBL11194928 | 0.77 | HSP90AA1 (0.68) | HSP90AA1MAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL5524404 | 0.76 | PDE7A (0.39) | HSP90AA1MAPK1KDM4EHPGDKMT2A | |
| SCHEMBL13903600 | 0.74 | HSP90AA1 (0.49) | HSP90AA1MAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL5236007 | 0.74 | HSP90AA1 (0.52) | HSP90AA1MAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL7701876 | 0.71 | RAB9A (0.43) | HSP90AA1MAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL4225977 | 0.70 | HSP90AA1 (0.45) | HSP90AA1MAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL4086070 | 0.70 | HSP90AA1 (1.00) | HSP90AA1MAPK1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2092824-A1 | Heterocyclyl pyrimidines | Bayer CropScience AG (DE) | 2009-08-26 | — | — | EP | disclosed |