Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.41 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17102309 | 0.85 | LMNA (0.64) | CYP11B1CYP11B2CYP19A1L3MBTL1LMNA | |
| SCHEMBL26129994 | 0.83 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1L3MBTL1LMNA | |
| SCHEMBL23120688 | 0.79 | HSP90AA1 (0.48) | CYP11B1CYP11B2CYP19A1L3MBTL1LMNA | |
| SCHEMBL31434521 | 0.78 | CYP11B1 (0.42) | CYP11B1CYP11B2CYP19A1L3MBTL1LMNA | |
| SCHEMBL27463321 | 0.78 | CYP11B1 (0.42) | CYP11B1CYP11B2CYP19A1L3MBTL1LMNA | |
| SCHEMBL23831139 | 0.78 | KCNH2 (0.48) | CYP11B1CYP11B2CYP19A1L3MBTL1LMNA | |
| SCHEMBL26128312 | 0.78 | KCNH2 (0.48) | CYP11B1CYP11B2CYP19A1LMNACYP1A2 | |
| SCHEMBL5532942 | 0.77 | LMNA (0.36) | CYP11B1CYP11B2CYP19A1HSD17B10L3MBTL1 | |
| SCHEMBL20762560 | 0.75 | BRD4 (0.48) | CYP11B1CYP11B2CYP19A1HSD17B10L3MBTL1 | |
| SCHEMBL30195058 | 0.75 | HSP90AA1 (0.41) | CYP11B1CYP11B2CYP19A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120261650-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2012-10-18 | — | — | US | disclosed |
| US-20120261650-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2012-10-18 | — | — | US | disclosed |
| US-20120261650-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2012-10-18 | — | — | US | disclosed |
| WO-2012051666-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120261650-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | EBPL, PAICS, CCNL2 | CYP11B1 2622/4885CYP11B2 2014/4885CYP19A1 3194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.