Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 15/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | APOB | P04114 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727582 | 0.91 | MTTP (0.48) | MTTPGAAKDM4EALDH1A1LMNA | |
| SCHEMBL3727587 | 0.89 | MTTP (0.46) | MTTPGAAKDM4EALDH1A1LMNA | |
| SCHEMBL8612390 | 0.83 | MTTP (0.59) | MTTPGAAKDM4EALDH1A1LMNA | |
| SCHEMBL8609977 | 0.82 | KDM4E (0.59) | MTTPGAAKDM4EALDH1A1LMNA | |
| SCHEMBL7342820 | 0.80 | KDM4E (0.61) | MTTPGAAKDM4EALDH1A1LMNA | |
| SCHEMBL3726876 | 0.78 | SMN1; SMN2 (0.48) | MTTPGAAALDH1A1LMNAMAPT | |
| SCHEMBL3723677 | 0.78 | APOB (0.47) | MTTPGAAALDH1A1LMNAMAPT | |
| SCHEMBL3730634 | 0.77 | MTTP (0.43) | MTTPALDH1A1APOB | |
| SCHEMBL5528942 | 0.75 | MTTP (0.49) | MTTPAPOBSMN1; SMN2 | |
| SCHEMBL3730445 | 0.74 | KDM4E (0.46) | MTTPGAAKDM4EAPOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806149-A1 | SOLID MEDICINAL PREPARATION IMPROVED IN SOLUBILITY AND STABILITY AND PROCESS FOR PRODUCING THE SAME | Japan Tobacco, Inc. (JP) | 2007-07-11 | — | — | EP | disclosed |