Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL367909 | 0.97 | KMT2A (0.33) | KMT2AFFAR3LCKFYN | |
| Hydrochloric Acid SCHEMBL5533668 | 0.94 | KMT2A (0.32) | KMT2AFFAR3LCKFYN | |
| Water SCHEMBL5533666 | 0.94 | KMT2A (0.32) | KMT2AFFAR3LCKFYN | |
| SCHEMBL146863 | 0.94 | — | — | |
| SCHEMBL347378 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL7067135 | 0.92 | KMT2A (0.33) | KMT2AFFAR3LCKFYN | |
| Bromide SCHEMBL1697366 | 0.92 | KMT2A (0.38) | KMT2AFFAR3LCKFYN | |
| Hydrochloric Acid SCHEMBL4594095 | 0.92 | KMT2A (0.33) | KMT2AFFAR3LCKFYN | |
| Iodide SCHEMBL7215913 | 0.92 | KMT2A (0.33) | KMT2AFFAR3LCKFYN | |
| Water SCHEMBL28256104 | 0.92 | KMT2A (0.33) | KMT2AFFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370220-B1 | SHAMPOO COMPOSITIONS | UNILEVER PLC (GB) | 2007-06-06 | — | — | EP | disclosed |
| US-20020192180-A1 | Shampoo compositions | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2002-12-19 | — | — | US | disclosed |
| WO-1999066886-A1 | ANTIMICROBIAL HAIR TREATMENT COMPOSITION | UNILEVER PLC (GB) | 1999-12-29 | — | — | WO | disclosed |
| WO-1997039096-A1 | ANTIMICROBIAL HAIR TREATMENT COMPOSITION | OLIN CORPORATION (US) | 1997-10-23 | — | — | WO | disclosed |