Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.39 |
| ▸ | F2 | P00734 | 13/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537319 | 0.95 | F10 (0.38) | F10F2KCNH2 | |
| SCHEMBL5533724 | 0.93 | F10 (0.38) | F10F2KCNH2 | |
| SCHEMBL5530280 | 0.93 | F10 (0.40) | F10F2 | |
| SCHEMBL5530355 | 0.90 | F10 (0.41) | F10F2KLKB1ELANE | |
| SCHEMBL5532082 | 0.90 | F2 (0.36) | F10F2KLKB1 | |
| SCHEMBL5534413 | 0.86 | F10 (0.37) | F10F2KCNH2 | |
| SCHEMBL5531803 | 0.86 | F10 (0.36) | F10F2KCNH2 | |
| SCHEMBL5532201 | 0.85 | RAB9A (0.40) | F10F2KCNH2 | |
| SCHEMBL5555126 | 0.84 | F10 (0.40) | F10F2KCNH2 | |
| SCHEMBL5532926 | 0.84 | F10 (0.40) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373194-B1 | BENZAMIDE INHIBITORS OF FACTOR Xa | MILLENNIUM PHARM INC (US) | 2007-08-01 | — | — | EP | claimed |
| EP-1373194-A1 | BENZAMIDE INHIBITORS OF FACTOR Xa | Millennium Pharmaceuticals, Inc. (US) | 2004-01-02 | — | — | EP | claimed |
| WO-2002079145-A1 | BENZAMIDE INHIBITORS OF FACTOR Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-10-10 | — | — | WO | claimed |
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1373194-B1 | BENZAMIDE INHIBITORS OF FACTOR Xa | MILLENNIUM PHARM INC (US) | 2007-08-01 | — | — | EP | disclosed |