⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10484390 | 0.84 | ALOX5 (0.43) | — | |
| SCHEMBL24017099 | 0.81 | ALOX5 (0.40) | — | |
| SCHEMBL24017032 | 0.81 | ALOX5 (0.40) | — | |
| SCHEMBL1488680 | 0.80 | — | — | |
| SCHEMBL105608 | 0.80 | ALOX5 (0.41) | — | |
| SCHEMBL13138026 | 0.77 | TDP1 (0.45) | — | |
| SCHEMBL12489667 | 0.76 | — | — | |
| SCHEMBL2030838 | 0.75 | ALOX5 (0.47) | — | |
| SCHEMBL11329381 | 0.75 | — | — | |
| SCHEMBL79717 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759575-B | Preparation method of clopidogrel hydrogen sulfate and intermediate N- (2-thienylethyl) methylamine thereof | 武汉武药制药有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-112759575-A | Preparation method of clopidogrel hydrogen sulfate and intermediate N- (2-thienylethyl) methylene thereof | 武汉武药制药有限公司 | 2021-05-07 | — | — | CN | claimed |
| CN-112759575-B | Preparation method of clopidogrel hydrogen sulfate and intermediate N- (2-thienylethyl) methylamine thereof | 武汉武药制药有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-112759575-B | Preparation method of clopidogrel hydrogen sulfate and intermediate N- (2-thienylethyl) methylamine thereof | 武汉武药制药有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-112759575-B | Preparation method of clopidogrel hydrogen sulfate and intermediate N- (2-thienylethyl) methylamine thereof | 武汉武药制药有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-112759575-A | Preparation method of clopidogrel hydrogen sulfate and intermediate N- (2-thienylethyl) methylene thereof | 武汉武药制药有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-112759575-A | Preparation method of clopidogrel hydrogen sulfate and intermediate N- (2-thienylethyl) methylene thereof | 武汉武药制药有限公司 | 2021-05-07 | — | — | CN | disclosed |
| WO-2021018195-A1 | NOVEL TRICYCLIC COMPOUNDS AS BCR-ABL INHIBITORS | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2021-02-04 | — | — | WO | disclosed |
| US-8354406-B2 | Chemical compounds | GLAXOSMITHKLINE LLC (US) | 2013-01-15 | — | — | US | disclosed |
| US-20120035164-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC | 2012-02-09 | — | — | US | disclosed |
| US-8063071-B2 | Chemical compounds | GlaxoSmithKline, LLC (US) | 2011-11-22 | — | — | US | disclosed |
| US-20090143372-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC | 2009-06-04 | — | — | US | disclosed |
| EP-1896014-A2 | CHEMICAL COMPOUNDS | Smithkline Beecham Corporation (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007005534-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-01-11 | — | — | WO | disclosed |
| US-6258961-B1 | A 2-((2-THIENYL)ETHYLAMINO)-(2-HALOGENPHENYL)ACETAMIDE | SANOFI-SYNTHELABO (FR) | 2001-07-10 | — | — | US | disclosed |