SCHEMBL5536055

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5546258	0.86	ALDH1A1 (0.49)	KMT2AMEN1L3MBTL1
	SCHEMBL14415491	0.77	PRSS1 (0.46)	KDM4ELMNAPRSS1TPSAB1MAOB
	SCHEMBL5540914	0.75	HTR2A (0.40)	KDM4ELMNAPRSS1TPSAB1MAOB
	SCHEMBL14415493	0.75	POLB (0.50)	KDM4ELMNAPRSS1TPSAB1MAOB
	SCHEMBL5546397	0.74	HTR2A (0.42)	KDM4ELMNAHTR2AKMT2AMEN1
	SCHEMBL5545459	0.73	KCNH2 (0.51)	LMNAHTR2ASMN1; SMN2
	SCHEMBL14415494	0.72	SMN1; SMN2 (0.50)	KDM4ELMNAPRSS1TPSAB1MAOB
	SCHEMBL5535350	0.72	MAPT (0.40)	LMNAKMT2AMEN1MMP1MMP2
	SCHEMBL5360275	0.69	ALDH1A1 (0.64)	KDM4ELMNAMAOBKMT2AMEN1
	SCHEMBL22611647	0.69	IDO1 (0.41)	KDM4ELMNAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.