Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | GPR6 | P46095 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5532833 | 0.92 | KCNH2 (0.42) | KCNH2F10F2GPR6ALDH1A1 | |
| SCHEMBL5539613 | 0.91 | F10 (0.40) | KCNH2F10F2ALDH1A1KDM4E | |
| SCHEMBL5528334 | 0.91 | KCNH2 (0.44) | KCNH2F10F2GPR6ALDH1A1 | |
| SCHEMBL5528341 | 0.91 | KCNH2 (0.44) | KCNH2F10F2GPR6ALDH1A1 | |
| SCHEMBL5534005 | 0.90 | KCNH2 (0.41) | KCNH2F10F2GPR6ALDH1A1 | |
| SCHEMBL5532890 | 0.88 | KCNH2 (0.53) | KCNH2F10F2ALDH1A1KDM4E | |
| SCHEMBL5532886 | 0.88 | KCNH2 (0.53) | KCNH2F10F2ALDH1A1KDM4E | |
| SCHEMBL5535057 | 0.83 | F10 (0.35) | F10GPR6ALDH1A1KDM4EKMT2A | |
| SCHEMBL5534263 | 0.83 | F10 (0.41) | KCNH2F10F2ALDH1A1KDM4E | |
| SCHEMBL5531800 | 0.81 | F10 (0.41) | KCNH2F10F2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373194-B1 | BENZAMIDE INHIBITORS OF FACTOR Xa | MILLENNIUM PHARM INC (US) | 2007-08-01 | — | — | EP | claimed |