Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5534263 | 0.92 | F10 (0.41) | F10F2KDM4EALDH1A1MAPT | |
| SCHEMBL5536595 | 0.91 | KCNH2 (0.39) | F10F2KDM4EALDH1A1MAPT | |
| SCHEMBL5535298 | 0.91 | F10 (0.41) | F10F2KDM4EALDH1A1MAPT | |
| SCHEMBL5531800 | 0.91 | F10 (0.41) | F10F2KDM4EALDH1A1MAPT | |
| SCHEMBL5534467 | 0.90 | F10 (0.48) | F10F2KCNH2 | |
| SCHEMBL5537249 | 0.87 | KCNH2 (0.48) | F10F2KDM4EALDH1A1KMT2A | |
| SCHEMBL5532158 | 0.87 | KCNH2 (0.48) | F10F2KDM4EALDH1A1KMT2A | |
| SCHEMBL5529711 | 0.86 | F10 (0.52) | F10F2KDM4EALDH1A1MAPT | |
| SCHEMBL5541042 | 0.83 | F10 (0.47) | F10F2 | |
| SCHEMBL5532833 | 0.83 | KCNH2 (0.42) | F10F2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373194-B1 | BENZAMIDE INHIBITORS OF FACTOR Xa | MILLENNIUM PHARM INC (US) | 2007-08-01 | — | — | EP | claimed |