SCHEMBL5536624

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2851056	0.81	NPC1 (0.51)	POLBMAPK1ALDH1A1LMNAKMT2A
	SCHEMBL16140281	0.72	ALDH1A1 (0.65)	POLBMAPK1APPALDH1A1LMNA
	SCHEMBL25187033	0.72	MAPK1 (0.74)	POLBMAPK1APPALDH1A1LMNA
	SCHEMBL167524	0.72	MAPK1 (0.74)	POLBMAPK1APPALDH1A1LMNA
	SCHEMBL512152	0.71	CYP1A2 (0.46)	ALDH1A1LMNANOTUMGAAHSD17B10
	SCHEMBL5539585	0.71	NPC1 (0.39)	POLBALDH1A1LMNANOTUMHSD17B10
	SCHEMBL6423919	0.71	CA1 (0.67)	POLBMAPK1APPALDH1A1LMNA
	SCHEMBL28198	0.71	CA1 (0.67)	POLBMAPK1APPALDH1A1LMNA
	Water SCHEMBL4868802	0.70	MAPK1 (0.71)	POLBMAPK1APPALDH1A1LMNA
	SCHEMBL28375748	0.70	MAPK1 (0.71)	POLBMAPK1APPALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.