SCHEMBL553697

SCHEMBL553697

Cc1ccc2oc(C=Cc3nc4cc(C)ccc4o3)nc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.68
NPC1 O15118 7/20 0.56
RAB9A P51151 7/20 0.56
KDM4E B2RXH2 6/20 0.56
ALDH1A1 P00352 6/20 0.56
HPGD P15428 5/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
HSD17B10 Q99714 4/20 0.56
TP53 P04637 3/20 0.56
ATP4A P20648 2/20 0.53
ATP4B P51164 2/20 0.53
CASP3 P42574 2/20 0.53
SENP7 Q9BQF6 2/20 0.53
SENP6 Q9GZR1 2/20 0.53
POLB P06746 1/20 0.53
SENP8 Q96LD8 1/20 0.53
MAPT P10636 5/20 0.49
NFKB1 P19838 3/20 0.47
NFKB2 Q00653 3/20 0.47
RELA Q04206 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14579739 1.00 SNCA (0.68) SNCANPC1RAB9AKDM4EALDH1A1
SCHEMBL23827506 1.00 SNCA (0.68) SNCANPC1RAB9AKDM4EALDH1A1
SCHEMBL553696 1.00 SNCA (0.68) SNCANPC1RAB9AKDM4EALDH1A1
SCHEMBL29924040 1.00 SNCA (0.68) SNCANPC1RAB9AKDM4EALDH1A1
SCHEMBL30487871 1.00 SNCA (0.68) SNCANPC1RAB9AKDM4EALDH1A1
SCHEMBL27045570 0.92 SNCA (0.59) SNCANPC1RAB9AKDM4EALDH1A1
SCHEMBL28510184 0.89 SNCA (0.64) SNCANPC1RAB9AKDM4EALDH1A1
SCHEMBL8346086 0.86 NPC1 (0.58) SNCANPC1RAB9AKDM4EALDH1A1
SCHEMBL28820824 0.86 SNCA (0.61) SNCANPC1RAB9AKDM4EALDH1A1
SCHEMBL29952434 0.85 SNCA (0.56) SNCANPC1RAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090129053-A1 LIGHT-ENHANCED ELEMENT LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. (TW) 2009-05-21 US claimed
EP-1996760-A1 WHITENER FOR POLYESTER FABRICS DYLON INTERNATIONAL LIMITED (GB) 2008-12-03 EP claimed
US-20080272338-A1 DYE LOADED ZEOLITE MATERIAL UNIVERSITAET BERN (CH) 2008-11-06 US claimed
US-7372012-B2 Dye loaded zeolite material containing devices UNIVERSITAET BERN (CH) 2008-05-13 US claimed
WO-2007104916-A1 WHITENER FOR POLYESTER FABRICS DYLON INTERNATIONAL LIMITED (GB) 2007-09-20 WO claimed
US-20070159062-A1 Light-enhanced element LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. 2007-07-12 US claimed
EP-1335879-B1 DYE LOADED ZEOLITE MATERIAL UNIV BERN (CH) 2007-01-03 EP claimed
US-20060001004-A1 Dye loaded zeolite material containing devices UNIVERSITAET BERN (CH) 2006-01-05 US claimed
US-6932919-B2 Dye loaded zeolite material UNIVERSITAET BERN (CH) 2005-08-23 US claimed
US-20040026662-A1 Dye loaded zeolite material UNIVERSITAET BERN (CH) 2004-02-12 US claimed
US-6258370-B1 APPLYING OPTICAL BRIGHTENER WITH INTENSE FLUORESCENCE IN ULTRAVIOLET RADIATION; MONITORING SKIN; FREE OF FLUOROALIPHATIC SURFACTANT AND REDUCING AGENT AIR LIQUIDE SANTE (INTERNATIONAL) (FR) 2001-07-10 US claimed
EP-0136259-B1 4-HETEROCYCLYL-VINYL-4'-STYRYL-BIPHENYLS CIBA-GEIGY AG (CH) 1988-06-15 EP claimed
US-4666627-A FLUORESCENT BRIGHTENERS CIBA-GEIGY CORPORATION (US) 1987-05-19 US claimed
EP-3882702-B1 FLUORESCENT WHITE TONERS AND RELATED METHODS XEROX CORP (US) 2026-01-28 EP disclosed
US-12465559-B2 Fluorescent curable dental composition and cured product thereof KURARAY NORITAKE DENTAL INC. (JP) 2025-11-11 US disclosed
EP-3882703-B1 FLUORESCENT METALLIC TONERS AND RELATED METHODS XEROX CORP (US) 2025-05-07 EP disclosed
US-3962116-A COMPOSITIONS OF OPTICAL BRIGHTNESS AND ALUMINOSILICATES AND METHODS OF THEIR PRODUCTION HENKEL & CIE G.M.B.H. (DT) 1976-06-08 US disclosed
US-3954643-A SULFONATE SURFACTANT, FATTY ACID SOAP, BUILDER HENKEL & CIE GMBH (DT) 1976-05-04 US disclosed
US-3943178-A WASHING AGENT HENKEL & CIE GMBH (DT) 1976-03-09 US disclosed
US-3931033-A ETHOXYLATED ALCOHOL, ALKALI METAL SOAP, SEQUESTERANT, SOLVENT, WATER HENKEL & CIE G.M.B.H. (DT) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12465559-B2 Fluorescent curable dental composition and cured product thereof BRD1, TBCA, BAZ1A SNCA 3558/4885NPC1 4490/4885RAB9A 2558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.