BAZ1A — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL4555048	1.00	4/20
SCHEMBL4555442	0.72	4/20
SCHEMBL1311061	0.69	4/20
SCHEMBL5641387	0.63	4/20
SCHEMBL397661	0.61	4/20
SCHEMBL4123299	0.57	4/20
Hydrochloric Acid (SCHEMBL1143150)	0.55	4/20
SCHEMBL1047211	0.73	3/20
SCHEMBL4733272	0.60	3/20
SCHEMBL1518948	0.60	3/20
SCHEMBL1381338	0.52	3/20
Hydrochloric Acid (SCHEMBL1143009)	0.49	3/20
Trifluoroacetic Acid (SCHEMBL4371778)	0.48	3/20
SCHEMBL4555093	0.73	2/20
SCHEMBL4122859	0.68	2/20
SCHEMBL5657895	0.67	2/20
SCHEMBL672979	0.64	2/20
SCHEMBL3180203	0.64	2/20
SCHEMBL4555024	0.64	2/20
SCHEMBL5487584	0.64	2/20

Clinical trials — most relevant to BAZ1A by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Compared the Efficacy and Safety of CDOP Combined With Chidamide and CDOP in de Novo Peripheral T Cell Lymphoma Patients	PHASE3	UNKNOWN
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS	PHASE2	COMPLETED
Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/Refractory Hodgkin's Lymphoma	PHASE1/PHASE2	COMPLETED
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma	PHASE2	WITHDRAWN
Study of the Beach Regimen on Relapsed/Refractory Acute Myeloid Leukemia (R/R AML)	PHASE2	ACTIVE_NOT_RECRUITING
A Study Evaluating Megestrol Acetate Modulation in Hormone Receptor Positive Advanced Breast Cancer	PHASE2	UNKNOWN
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure	PHASE2	COMPLETED
An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab	PHASE1/PHASE2	RECRUITING
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL	PHASE1/PHASE2	RECRUITING
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma	PHASE1/PHASE2	COMPLETED
Vorinostat in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma	PHASE2	COMPLETED
Phase 1/ Phase 2 Study to Assess Safety and Efficacy of Orally Administered JBI-802 in Subjects With Myeloproliferative Neoplasms (MPN) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) With Thrombocytosis	PHASE1/PHASE2	RECRUITING
5-azacytidine Valproic Acid and ATRA in AML and High Risk MDS	PHASE2	COMPLETED
Vorinostat in Children	PHASE1/PHASE2	COMPLETED
A First-in-Human Study of JAB-8263 in Adult Patients With Advanced Solid Tumors	PHASE1	COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load	PHASE1	COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome	PHASE1	COMPLETED
Safety and Pharmacokinetic Profile of CKD-581	PHASE1	COMPLETED
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia	nan	UNKNOWN
Characterization of Microbiological and Genetic Features in Prostate Cancer and Their Association with Disease Stage	nan	ENROLLING_BY_INVITATION
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics	nan	UNKNOWN
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients	nan	RECRUITING
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Gene Expression in Predicting Response to Paclitaxel in Patients With Breast Cancer	nan	UNKNOWN
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma	nan	UNKNOWN
Detection of IKZF1 Deletion Mutation in Patients With Acute Lymphoblastic Leukemia and Its Impact in Therapy	nan	UNKNOWN
Study of Proteins in Head and Neck Cancer Cells	nan	COMPLETED
CMOP Regimen and Chidamide in the Treatment of Newly Diagnosed Peripheral T-cell Lymphoma	nan	UNKNOWN
Better Delineation of BCL11B Related Phenotype and Epigenetic Signature.	nan	COMPLETED
Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a BAZ1A binder may also engage these)

Protein	Name	Similarity
O88379	—	1.000	O88379 →
A8DZJ1	—	1.000	A8DZJ1 →
Q9Z277	—	1.000	Q9Z277 →
A0JMK9	—	0.997	A0JMK9 →
A2BIL7	—	0.996	A2BIL7 →
BPTF	Nucleosome-remodeling factor subunit BPTF	0.996	landscape →
Q9UIG0	—	0.995	Q9UIG0 →
Q1LYM3	—	0.995	Q1LYM3 →
Q17QK1	—	0.995	Q17QK1 →
Q6DD45	—	0.995	Q6DD45 →
A7YDW0	—	0.994	A7YDW0 →
Q9Y2H2	—	0.994	Q9Y2H2 →
F4K4J0	—	0.994	F4K4J0 →
Q9Z1T6	—	0.993	Q9Z1T6 →
Q9CSP9	—	0.993	Q9CSP9 →
Q92539	—	0.993	Q92539 →
Q7Z401	—	0.993	Q7Z401 →
KDM5B	Lysine-specific demethylase 5B	0.993	landscape →
Q8C0I4	—	0.993	Q8C0I4 →
Q14D04	—	0.993	Q14D04 →
A8E7C5	—	0.993	A8E7C5 →
B3H615	—	0.993	B3H615 →
DHX29	ATP-dependent RNA helicase DHX29	0.993	landscape →
Q5S003	—	0.993	Q5S003 →
Q8BMD7	—	0.993	Q8BMD7 →
Q5PQS3	—	0.993	Q5PQS3 →
Q9Z2U2	—	0.993	Q9Z2U2 →
Q6ZPS6	—	0.993	Q6ZPS6 →
Q5RAY1	—	0.993	Q5RAY1 →
P61406	—	0.993	P61406 →