SCHEMBL5537229

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5537237	0.77	PKM (0.43)	NR3C2HSP90AA1JAK2JAK1TYK2
	SCHEMBL15554413	0.77	NR3C2 (0.40)	NR3C2HSP90AA1JAK2JAK1TYK2
	SCHEMBL14696532	0.77	HSP90AA1 (0.44)	NR3C2HSP90AA1JAK2JAK1TYK2
	SCHEMBL10992734	0.77	POLB (0.55)	NR3C2HSP90AA1JAK2JAK1TYK2
	Hydrochloric Acid SCHEMBL11473793	0.76	POLB (0.53)	NR3C2HSP90AA1JAK2JAK1TYK2
	SCHEMBL29452537	0.74	NR3C2 (0.53)	NR3C2HSP90AA1JAK2JAK1TYK2
	SCHEMBL28026330	0.72	MAPK14 (0.49)	NR3C2MGLLPKMMAPK14MAPK11
	SCHEMBL15428604	0.70	NR3C2 (0.50)	NR3C2HSP90AA1JAK2JAK1TYK2
	SCHEMBL20897191	0.70	HSP90AA1 (0.51)	NR3C2HSP90AA1JAK2JAK1TYK2
	SCHEMBL27610654	0.68	KCNN4 (0.51)	KCNN4BCHEP2RX7TSHRNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.