SCHEMBL5537286

SCHEMBL5537286

N=C(N)NNP(=O)(O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL19458455 0.79 CA4 (0.30)
Phosphoric Acid SCHEMBL29559527 0.79 CA4 (0.30)
SCHEMBL11814327 0.74
Phosphoric Acid SCHEMBL11095763 0.72 TSHR (0.33)
SCHEMBL858254 0.71
Pyrophosphoric Acid SCHEMBL19458364 0.70 FDPS (0.53)
SCHEMBL28303446 0.69
SCHEMBL28034541 0.69
SCHEMBL28582167 0.69
Hydrogen Sulfide SCHEMBL27864758 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070123496-A1 Use of aminoguanidine or aminoguanidine analogs for the treatment of diseases of the nervous system KADDURAH-DAOUK RIMA 2007-05-31 US disclosed
US-20070123496-A1 Use of aminoguanidine or aminoguanidine analogs for the treatment of diseases of the nervous system KADDURAH-DAOUK RIMA 2007-05-31 US disclosed
US-20030018082-A1 Use of aminoguanidine or aminoguanidine analogs for the treatment of diseases of the nervous system KADDURAH-DAOUK RIMA (US) 2003-01-23 US disclosed
US-20030018082-A1 Use of aminoguanidine or aminoguanidine analogs for the treatment of diseases of the nervous system KADDURAH-DAOUK RIMA (US) 2003-01-23 US disclosed
US-6288124-B1 Methods of inhibiting undesirable cell growth using an aminoguanidine compound KADDURAH-DAOUK RIMA (US) 2001-09-11 US disclosed
US-6169115-B1 SUBSTRATES OR SUBSTRATE ANALOGS FOR CREATINE KINASE; KADDURAH-DAOUK RIMA (US) 2001-01-02 US disclosed
US-6169115-B1 SUBSTRATES OR SUBSTRATE ANALOGS FOR CREATINE KINASE; KADDURAH-DAOUK RIMA (US) 2001-01-02 US disclosed