Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.67 |
| ▸ | CTSD | P07339 | 1/20 | 0.67 |
| ▸ | CTSE | P14091 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537522 | 1.00 | REN (0.67) | RENCTSDCTSECYP3A4 | |
| SCHEMBL5537504 | 1.00 | REN (0.67) | RENCTSDCTSECYP3A4 | |
| SCHEMBL5076986 | 0.91 | REN (0.56) | RENCTSDCTSECYP3A4 | |
| SCHEMBL5076994 | 0.91 | REN (0.56) | RENCTSDCTSECYP3A4 | |
| SCHEMBL6432041 | 0.91 | REN (0.56) | RENCTSDCTSECYP3A4 | |
| SCHEMBL5081106 | 0.91 | REN (0.56) | RENCTSDCTSECYP3A4 | |
| SCHEMBL6432046 | 0.91 | REN (0.56) | RENCTSDCTSECYP3A4 | |
| SCHEMBL5076989 | 0.91 | REN (0.56) | RENCTSDCTSECYP3A4 | |
| SCHEMBL5466055 | 0.89 | REN (0.67) | RENCTSDCTSECYP3A4 | |
| SCHEMBL5466052 | 0.89 | REN (0.67) | RENCTSDCTSECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824851-A2 | NOVEL DIAZABICYCLONONENE DERIVATIVE | Actelion Pharmaceuticals Ltd. (CH) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006061791-A2 | NOVEL DIAZABICYCLONONENE DERIVATIVE | ACTELION PHARMACEUTICALS LTD (CH) | 2006-06-15 | — | — | WO | disclosed |