Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL876466 | 1.00 | ALDH1A1 (0.74) | ALDH1A1KMT2APOLBTSHRCA12 | |
| Iodide SCHEMBL3474173 | 1.00 | ALDH1A1 (0.74) | ALDH1A1KMT2APOLBTSHRCA12 | |
| Iodide SCHEMBL5533691 | 1.00 | ALDH1A1 (0.74) | ALDH1A1KMT2APOLBTSHRCA12 | |
| SCHEMBL82664 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL28763275 | 0.96 | KMT2A (0.74) | ALDH1A1KMT2APOLBTSHRCA12 | |
| Hydrochloric Acid SCHEMBL28337026 | 0.96 | KMT2A (0.74) | ALDH1A1KMT2APOLBTSHRCA12 | |
| Bromide SCHEMBL28812312 | 0.96 | ALDH1A1 (0.74) | ALDH1A1KMT2APOLBTSHRCA12 | |
| Ammonia Solution, Strong SCHEMBL14645160 | 0.96 | ALDH1A1 (0.74) | ALDH1A1KMT2APOLBTSHRCA12 | |
| Dimethylamine SCHEMBL8078055 | 0.92 | KMT2A (0.69) | ALDH1A1KMT2APOLBTSHRCA12 | |
| Iodide SCHEMBL1226180 | 0.88 | ALDH1A1 (0.96) | ALDH1A1KMT2APOLBTSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060021647-A1 | Molecular photovoltaics, method of manufacture and articles derived therefrom | SABIC INNOVATIVE PLASTICS IP B.V. | 2006-02-02 | — | — | US | claimed |
| EP-1752497-A2 | Organic dye compositions and use thereof in photovoltaic cells | GENERAL ELECTRIC COMPANY (US) | 2007-02-14 | — | — | EP | disclosed |
| US-20070028961-A1 | Organic dye compositions and use thereof in photovoltaic cells | GENERAL ELECTRIC COMPANY | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070028961-A1 | Organic dye compositions and use thereof in photovoltaic cells | CROCC, EPCAM, CD99 | ALDH1A1 595/4885KMT2A 3607/4885POLB 4158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.