Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5539442 | 1.00 | ERN1 (0.32) | ERN1PTP4A3NFE2L2CES2CES1 | |
| SCHEMBL15145958 | 0.74 | ERN1 (0.32) | ERN1PTP4A3NFE2L2CES2CES1 | |
| SCHEMBL3193831 | 0.74 | ERN1 (0.32) | ERN1PTP4A3NFE2L2CES2CES1 | |
| SCHEMBL320358 | 0.72 | ERN1 (0.34) | ERN1PTP4A3CES2CES1 | |
| SCHEMBL2091124 | 0.71 | ERN1 (0.37) | ERN1PTP4A3NFE2L2CES2CES1 | |
| SCHEMBL2094779 | 0.70 | PTGS1 (0.46) | NFE2L2CES2CES1 | |
| SCHEMBL2094782 | 0.70 | PTGS1 (0.46) | NFE2L2CES2CES1 | |
| SCHEMBL21676194 | 0.70 | ERN1 (0.39) | ERN1PTP4A3CES2CES1 | |
| SCHEMBL1673714 | 0.69 | NQO2 (0.31) | NFE2L2 | |
| SCHEMBL1689618 | 0.69 | NFE2L2 (0.61) | NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |