Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14785734 | 0.87 | MAPT (0.82) | KDM4EALDH1A1GAALMNATSHR | |
| SCHEMBL19275979 | 0.84 | KDM4E (0.74) | KDM4EALDH1A1GAALMNATSHR | |
| SCHEMBL227741 | 0.83 | KDM4E (0.74) | KDM4EALDH1A1GAALMNATSHR | |
| SCHEMBL30496676 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1GAALMNATSHR | |
| SCHEMBL27154648 | 0.81 | KDM4E (0.71) | KDM4EALDH1A1GAALMNATSHR | |
| SCHEMBL20715593 | 0.81 | MAPT (0.73) | KDM4EALDH1A1GAALMNATSHR | |
| SCHEMBL5310612 | 0.81 | KDM4E (0.78) | KDM4EALDH1A1GAALMNATSHR | |
| SCHEMBL3633839 | 0.80 | MAPT (0.67) | KDM4EALDH1A1GAALMNATSHR | |
| SCHEMBL14363381 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1GAALMNATSHR | |
| SCHEMBL20736552 | 0.80 | MAPT (0.53) | KDM4EALDH1A1GAALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217800-B2 | Peptide leukotriene receptor | ASTELLAS PHARMA INC. (JP) | 2007-05-15 | — | — | US | disclosed |
| EP-1614425-A2 | Leukotriene receptor antagonist | Astellas Pharma Inc. (JP) | 2006-01-11 | — | — | EP | disclosed |
| EP-1213353-B1 | PEPTIDE LEUKOTRIENE RECEPTOR | ASTELLAS PHARMA INC (JP) | 2005-11-16 | — | — | EP | disclosed |
| US-6878525-B1 | Peptide leukotriene receptor | YAMANOUCHI PHARMACEUTICAL CO, LTD. (JP) | 2005-04-12 | — | — | US | disclosed |
| US-20050037968-A1 | Peptide leukotriene receptor | YAMANOUCHI PHARMACEUTICAL CO., LTD., HELIX RESEARCH INSTITUTE | 2005-02-17 | — | — | US | disclosed |
| EP-1213353-A1 | PEPTIDE LEUKOTRIENE RECEPTOR | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |