Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353455 | 0.80 | TDP1 (0.54) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL37064 | 0.80 | TDP1 (0.54) | TDP1ATML3MBTL1ALOX15HPGD | |
| Diphenyl Ethanedioat SCHEMBL43364 | 0.80 | TDP1 (0.54) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL9748734 | 0.80 | LTA4H (0.45) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL18073 | 0.80 | TDP1 (0.54) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL9353461 | 0.80 | TDP1 (0.54) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL9241160 | 0.80 | TDP1 (0.54) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL27352197 | 0.80 | TDP1 (0.54) | TDP1ATML3MBTL1ALOX15HPGD | |
| SCHEMBL7566178 | 0.79 | MEN1 (0.48) | TDP1ALOX15HPGDHSD17B10MAPT | |
| SCHEMBL4544920 | 0.79 | TDP1 (0.48) | TDP1ATML3MBTL1ALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8406 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761567-A | Compositions and methods for modifying eukaryotic cells | 奥查德疗法(欧洲)有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-108780273-B | Photosensitive colored resin composition, color filter and manufacturing method thereof, and display device | DNP精细化工股份有限公司 | 2022-06-28 | — | — | CN | claimed |
| CN-114450412-A | Compositions and methods for modifying eukaryotic cells | 奥查德疗法(欧洲)有限公司 | 2022-05-06 | — | — | CN | claimed |
| WO-2021076993-A1 | COMPOSITIONS AND METHODS FOR MODIFYING EUKARYOTIC CELLS | ORCHARD THERAPEUTICS (EUROPE) LIMITED (GB) | 2021-04-22 | — | — | WO | claimed |
| WO-2020247814-A1 | COMPOSITIONS AND METHODS FOR MODIFYING EUKARYOTIC CELLS | ORCHARD THERAPEUTICS (EUROPE) LIMITED (GB) | 2020-12-10 | — | — | WO | claimed |
| US-9132130-B2 | Purine derivative and antitumor agent using same | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2015-09-15 | — | — | US | claimed |
| EP-2426130-B1 | PURINE DERIVATIVE AND ANTITUMOR AGENT USING SAME | ZENYAKU KOGYO KK (JP) | 2015-03-11 | — | — | EP | claimed |
| CN-102459269-B | Purine derivative and antitumor agent using same | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 2014-10-15 | — | — | CN | claimed |
| US-8846907-B2 | Spiro-condensed indoline derivatives as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2014-09-30 | — | — | US | claimed |
| US-20140179921-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-26 | — | — | US | claimed |
| US-4281115-A | DISPERSE DYES | SANDOZ LTD. (CH) | 1981-07-28 | — | — | US | claimed |
| US-4234488-A | FLUORESCENT DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-18 | — | — | US | claimed |
| US-4234482-A | Substituted 3-carbalkoxy 4-alkylamino-azobenzene compound as disperse dyestuffs for synthetic fibers | PRODUITS CHIMIQUES UGINE KUHLMANN SERVICE PROPRIETE INDUSTRIELLE (FR) | 1980-11-18 | — | — | US | claimed |
| US-4226863-A | BACTERICIDES, ANTIBIOTICS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-10-07 | — | — | US | claimed |
| US-4165373-A | ANTIBIOTICS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-08-21 | — | — | US | claimed |
| US-4147865-A | Benz-(C,D)-indolyl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-03 | — | — | US | claimed |
| US-4125611-A | MICROBIOCIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-11-14 | — | — | US | claimed |
| US-4010191-A | Acyl derivatives of substituted bis-arylalkylamino compounds | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-03-01 | — | — | US | claimed |
| US-3971740-A | DYES FOR POLYESTER FIBERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | claimed |
| US-3945989-A | Fluoro triazine containing water insoluble azo dyestuff | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | claimed |