SCHEMBL5540294

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5537903	0.91	CA1 (0.50)	CA1CA2ESR1ESR2CA12
	SCHEMBL5543523	0.89	ALDH1A1 (0.57)	ESR1ESR2LMNACYP1A2CYP3A4
	SCHEMBL5541265	0.88	CA1 (0.47)	CA1CA2ESR1ESR2CA12
	SCHEMBL5543889	0.84	CA1 (0.61)	CA1CA2ESR1ESR2CA12
	SCHEMBL5544367	0.84	CYP4A11 (0.58)	CA1CA2CA12CA7CA9
	SCHEMBL12199135	0.83	CA1 (0.68)	CA1CA2ESR1ESR2CA12
	SCHEMBL5539850	0.82	CYP4F2 (0.64)	CA1CA2CA12CA7CA9
	SCHEMBL7365104	0.81	ESR1 (0.56)	CA1CA2ESR1ESR2CA12
	SCHEMBL571227	0.80	CA1 (0.63)	CA1CA2ESR1ESR2CA12
	SCHEMBL5535661	0.80	ESR1 (0.57)	ESR1LMNACYP1A2CYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.