⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11330791 | 0.74 | — | — | |
| SCHEMBL1632255 | 0.74 | — | — | |
| SCHEMBL1086373 | 0.74 | — | — | |
| SCHEMBL6911336 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL11544165 | 0.70 | L3MBTL1 (0.40) | — | |
| SCHEMBL1358101 | 0.70 | — | — | |
| SCHEMBL1632254 | 0.70 | — | — | |
| SCHEMBL18500604 | 0.70 | — | — | |
| SCHEMBL6205744 | 0.67 | L3MBTL1 (0.42) | — | |
| SCHEMBL20138104 | 0.67 | L3MBTL1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765832-A1 | NOVEL OXABISPIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | AstraZeneca AB (SE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123748-A1 | NOVEL OXABISPIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2005-12-29 | — | — | WO | disclosed |