SCHEMBL5540685

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2616784	0.79	NOTUM (0.58)	MAPTALDH1A1MEN1GAAHPGD
	SCHEMBL2333530	0.78	MAPT (0.49)	MAPTALDH1A1MEN1GAAHPGD
	SCHEMBL3154176	0.78	MAPT (0.49)	MAPTALDH1A1MEN1GAAHPGD
	SCHEMBL13960939	0.76	MAPT (0.45)	MAPTALDH1A1MEN1GAAHPGD
	SCHEMBL2625777	0.76	NOTUM (0.57)	MAPTALDH1A1MEN1GAAHPGD
	SCHEMBL5501377	0.76	DRD2 (0.56)	MAPTALDH1A1MEN1GAAHPGD
	SCHEMBL2056315	0.76	SRD5A1 (0.46)	MAPTALDH1A1MEN1GAAHPGD
	SCHEMBL2625779	0.76	NOTUM (0.57)	MAPTALDH1A1MEN1GAAHPGD
	SCHEMBL14046652	0.76	MAPT (0.45)	MAPTALDH1A1MEN1GAAHPGD
	SCHEMBL17351956	0.76	SRD5A1 (0.46)	MAPTALDH1A1MEN1GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.