Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 9/20 | 0.37 |
| ▸ | CA2 | P00918 | 9/20 | 0.37 |
| ▸ | CA12 | O43570 | 8/20 | 0.37 |
| ▸ | CA9 | Q16790 | 8/20 | 0.37 |
| ▸ | CA7 | P43166 | 7/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 7/20 | 0.37 |
| ▸ | CA6 | P23280 | 6/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.37 |
| ▸ | CA5A | P35218 | 6/20 | 0.37 |
| ▸ | CA3 | P07451 | 5/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 5/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230505 | 0.89 | PDE4D (0.54) | PDE4DPDE3ACISD1POLBLMNA | |
| SCHEMBL29436060 | 0.88 | PDE4D (0.53) | PDE4DPDE3ACISD1POLBCA1 | |
| SCHEMBL231445 | 0.88 | PDE4D (0.53) | PDE4DPDE3ACISD1POLBCA1 | |
| SCHEMBL231731 | 0.88 | PDE4D (0.54) | PDE4DPDE3ACISD1POLBCA1 | |
| SCHEMBL230303 | 0.86 | PDE4D (0.58) | PDE4DPDE3ACISD1POLBCA1 | |
| SCHEMBL231240 | 0.85 | PDE4D (0.61) | PDE4DPDE3ACISD1POLBLMNA | |
| SCHEMBL12522803 | 0.85 | PDE4D (0.56) | PDE4DPDE3ACISD1POLBCA1 | |
| SCHEMBL230673 | 0.83 | PDE4D (0.58) | PDE4DPDE3ACISD1POLBCA1 | |
| SCHEMBL18993718 | 0.81 | PDE4D (0.59) | PDE4DPDE3ACISD1POLBLMNA | |
| SCHEMBL18993721 | 0.80 | PDE4D (0.62) | PDE4DPDE3ACISD1POLBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149526-A1 | Diuretic and diuretic-like compound analogs | NEUROTHERAPEUTICS PHARMA, L.L.C. | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149526-A1 | Diuretic and diuretic-like compound analogs | AQP4, AVPR2, AQP1 | PDE4D 89/4885PDE3A 125/4885CISD1 2281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.