Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CASK | O14936 | 1/20 | 0.42 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
| ▸ | FSHR | P23945 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5539930 | 0.93 | CYP2C19 (0.46) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL5547092 | 0.93 | CYP2C19 (0.46) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL5543248 | 0.93 | CYP2C19 (0.45) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL5546009 | 0.93 | CYP2C19 (0.46) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL5547250 | 0.92 | CYP2C19 (0.44) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL5539125 | 0.92 | CYP2C19 (0.45) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL5541025 | 0.91 | CYP2C19 (0.45) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL16009342 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL5538498 | 0.91 | CYP2C19 (0.44) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL5538937 | 0.90 | RXFP1 (0.42) | ALDH1A1KDM4EGAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070124152-A1 | Hiv Integrase Inhibitors | GLAXOSMITHKLINE LLC | 2007-05-31 | — | — | US | disclosed |