Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TNF | P01375 | 2/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5541041 | 0.94 | CNR2 (0.42) | CNR2HTTPOLBTDP1MEN1 | |
| SCHEMBL5540932 | 0.85 | MEN1 (0.43) | CNR2HTTPOLBTDP1MEN1 | |
| SCHEMBL5538489 | 0.83 | POLB (0.45) | CNR2HTTPOLBTDP1MEN1 | |
| SCHEMBL5538495 | 0.83 | POLB (0.45) | CNR2HTTPOLBTDP1MEN1 | |
| SCHEMBL5545917 | 0.83 | POLB (0.45) | CNR2HTTPOLBTDP1MEN1 | |
| SCHEMBL5540640 | 0.81 | MEN1 (0.48) | CNR2HTTPOLBTDP1MEN1 | |
| SCHEMBL5540538 | 0.80 | CNR2 (0.46) | CNR2HTTPOLBTDP1MEN1 | |
| SCHEMBL5545490 | 0.80 | MEN1 (0.47) | CNR2HTTPOLBTDP1MEN1 | |
| SCHEMBL5547431 | 0.79 | L3MBTL1 (0.39) | CNR2HTTPOLBTDP1MEN1 | |
| SCHEMBL5540681 | 0.79 | CNR2 (0.40) | CNR2HTTPOLBTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070124152-A1 | Hiv Integrase Inhibitors | GLAXOSMITHKLINE LLC | 2007-05-31 | — | — | US | disclosed |