Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS12 | P56730 | 20/20 | 1.00 |
| ▸ | F2 | P00734 | 1/20 | 0.63 |
| ▸ | F10 | P00742 | 1/20 | 0.63 |
| ▸ | PLG | P00747 | 1/20 | 0.63 |
| ▸ | PLAT | P00750 | 1/20 | 0.63 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724662 | 0.92 | PRSS12 (0.85) | PRSS12F2F10PLGPLAT | |
| SCHEMBL2721891 | 0.87 | PRSS12 (0.77) | PRSS12 | |
| SCHEMBL15717512 | 0.86 | PRSS12 (1.00) | PRSS12F2F10PLGPLAT | |
| SCHEMBL2723144 | 0.82 | PRSS12 (0.69) | PRSS12 | |
| SCHEMBL5538461 | 0.80 | PRSS12 (0.67) | PRSS12 | |
| SCHEMBL15717628 | 0.79 | PRSS12 (0.82) | PRSS12F2F10PLGPLAT | |
| SCHEMBL15717511 | 0.79 | PRSS12 (0.86) | PRSS12F2F10PLGPLAT | |
| SCHEMBL15717726 | 0.78 | PRSS12 (1.00) | PRSS12F2F10PLGPLAT | |
| SCHEMBL15717428 | 0.76 | PRSS12 (1.00) | PRSS12F2F10PLGPLAT | |
| SCHEMBL10243990 | 0.76 | PRSS12 (0.72) | PRSS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130261130-A1 | NEUROTRYPSIN INHIBITORS | NEUROTUNE AG (CH) | 2013-10-03 | — | — | US | disclosed |
| US-20130261130-A1 | NEUROTRYPSIN INHIBITORS | NEUROTUNE AG (CH) | 2013-10-03 | — | — | US | disclosed |
| WO-2012059442-A2 | NEUROTRYPSIN INHIBITORS | NEUROTUNE AG (CH) | 2012-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261130-A1 | NEUROTRYPSIN INHIBITORS | MTPN, CHRNA7, CHRNA10 | PRSS12 5/4885F2 4771/4885F10 3080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.